Studies on the effect of dietary phosphorus loading on the physiological function and determination of tolerable upper intake level of phosphorus in human.
- Conditions
- Chronic Kidney Disease, Cardiovascular disease, metabolic bone disease
- Registration Number
- JPRN-UMIN000000803
- Lead Sponsor
- Department of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima
- Brief Summary
When the subjects ingested high phosphorus diet (1200mg/meal), serum phosphorus levels significantly increased at 2 hours after the meal ingestion. In addition, flow-mediated dilation (%FMD) of subjects also significantly decreased at 2 hours after high phosphorus diet ingestion, but not changed after control diet ingestion. These results suggest that acute increase in serum phosphorus level may be involved in endothelial dysfunction.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Not provided
hyperlipidemia, hypertension, kidney dysfunction, diabetes, cardiovascular disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method