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Studies on the effect of dietary phosphorus loading on the physiological function and determination of tolerable upper intake level of phosphorus in human.

Not Applicable
Recruiting
Conditions
Chronic Kidney Disease, Cardiovascular disease, metabolic bone disease
Registration Number
JPRN-UMIN000000803
Lead Sponsor
Department of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima
Brief Summary

When the subjects ingested high phosphorus diet (1200mg/meal), serum phosphorus levels significantly increased at 2 hours after the meal ingestion. In addition, flow-mediated dilation (%FMD) of subjects also significantly decreased at 2 hours after high phosphorus diet ingestion, but not changed after control diet ingestion. These results suggest that acute increase in serum phosphorus level may be involved in endothelial dysfunction.

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Not provided

Exclusion Criteria

hyperlipidemia, hypertension, kidney dysfunction, diabetes, cardiovascular disease

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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