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Development of Rehabilitation Methods for Intermuscular Coordination after Stroke

Not Applicable
Recruiting
Conditions
Diseases of the circulatory system
Registration Number
KCT0005803
Lead Sponsor
Korea Advanced Institute of Science and Technology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
141
Inclusion Criteria

(1) at least 6 months after stroke onset
(2) unilateral ischemic or hemorrhagic stroke
(3) hemi-paresis

Exclusion Criteria

(1) Neurological disorder other than stroke
(2) Receiving botulinum toxin on the impaired arm within 3 months
(3) Cognitive dysfunction that precludes comprehension of experimental tasks and the provision of written informed consent (score lower than 18 on the Korean version of Mini-Mental Status Examination)
(4) Severe spasticity (Modified Ashworth <4)
(5) Sign of severe concurrent medical problems (including shoulder pain) sufficient to preclude repetitive reaching to targets (verbally asked during pre-screening)

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Muscle synergy (composition and activation of muscle synergies);Brain activity and functional connectivity of regions of interest;End-point force (direction, magnitude, and moment in 3D force space);Level of upper limb motor impairment (Fugl-Meyer Assessment);Upper limb motor function (Wolf Motor Function Test)
Secondary Outcome Measures
NameTimeMethod
pper limb joint motion (3D translation of glenohumeral joint center, 3 DOF rotation of shoulder and 1 DOF rotation of elbow
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