Development of Rehabilitation Methods for Intermuscular Coordination after Stroke
- Conditions
- Diseases of the circulatory system
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 141
(1) at least 6 months after stroke onset
(2) unilateral ischemic or hemorrhagic stroke
(3) hemi-paresis
(1) Neurological disorder other than stroke
(2) Receiving botulinum toxin on the impaired arm within 3 months
(3) Cognitive dysfunction that precludes comprehension of experimental tasks and the provision of written informed consent (score lower than 18 on the Korean version of Mini-Mental Status Examination)
(4) Severe spasticity (Modified Ashworth <4)
(5) Sign of severe concurrent medical problems (including shoulder pain) sufficient to preclude repetitive reaching to targets (verbally asked during pre-screening)
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Muscle synergy (composition and activation of muscle synergies);Brain activity and functional connectivity of regions of interest;End-point force (direction, magnitude, and moment in 3D force space);Level of upper limb motor impairment (Fugl-Meyer Assessment);Upper limb motor function (Wolf Motor Function Test)
- Secondary Outcome Measures
Name Time Method pper limb joint motion (3D translation of glenohumeral joint center, 3 DOF rotation of shoulder and 1 DOF rotation of elbow