Influence of Hematocrit Level on the Visibility of the Venous Network in Magnetic Susceptibility Imaging
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Specific influence of the hematocrit level on the visibility of the venous network
研究概览
简要总结
Magnetic susceptibility imaging is a magnetic resonance imaging (MRI) technique that uses the magnetic properties of tissues and the BOLD (blood oxygen level-dependent) effect. It allows a better visualization of venous structures and hemorrhagic lesions. These sequences are now used in clinical routine.
The extreme sensitivity of these sequences to the oxy/deoxyhemoglobin ratio makes it possible to describe a new MRI semiology, particularly in the context of cerebral ischemia. The interest of the analysis of the venous network signal, which can reflect cerebral perfusion, has been reported.
However, the influence of the hematocrit level on the signal of the venous network in magnetic susceptibility imaging has not been evaluated at present. It seems important to better define the influence of hematocrit level on the signal of the veins with this sequence to avoid potential diagnostic errors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient whose age ≥ 18 years
- •Patient referred to GHPSJ for suspected stroke
- •Patient who had a brain MRI including the magnetic susceptibility sequence
- •Patient for whom a blood count with hematocrit was performed at the same time (within 7 days between the MRI and the blood test)
- •French-speaking patient
排除标准
- •Patient under guardianship or curatorship
- •Patient deprived of liberty
- •Patient under court protection
- •Elimination of potential biases: recent injection (48 h) of gadolinium, pathology likely to modify the venous signal in magnetic susceptibility imaging (notably arterial occlusion or stenosis), high flow oxygenation, sickle cell disease, thalassemia.
- •Patient objecting to the use of his/her data for this research
结局指标
主要结局
Specific influence of the hematocrit level on the visibility of the venous network
时间窗: Day 1
This outcome corresponds to the visibility of the venous network in magnetic susceptibility imaging using a visual scale allowing comparison between patients with normal hematocrit, anemia or polycythemia.
次要结局
- Inter-observer agreement of the visual analysis of the venous network(Day 1)