Effects of SUDOKU Mind Activation & Revitalizing Training on Cognitive Function in People With Mild Cognitive Impairment

Not Applicable

Completed

• Conditions: Mild Cognitive Impairment
• Interventions: Behavioral: 24-week SUDOKU Training Programme; Other: Control Arm (wait-list)

• Registration Number: NCT04913857
• Lead Sponsor: The University of Hong Kong

Brief Summary

This study aims to implement a SUDOKU Mind Activation and Revitalization Training (SMART) Program to promote cognitive health among patients with mild cognitive impairment (MCI), and the use of active mind strategy in preventing dementia among the older adults. The SMART Program consists of two components including, a community empowerment-educational campaign on active mind strategies for older adults, and a 24-week SUDOKU Training Programme for people with MCI.

Detailed Description

This study aims to implement a SMART Program to promote cognitive health among patients with MCI, and the use of active mind strategy in preventing dementia among the older adults. The SMART Program consists of two components including, a community empowerment-educational campaign on active mind strategies for older adults, and a 24-week SUDOKU Training Programme for people with MCI.

The community empowerment-educational campaign will be conducted in the elderly care centres of the two collaborating non-governmental organizations, with the purpose of increasing the awareness of people aged 55 or above on the importance of maintaining an active mind and preventing age-related cognitive decline and dementia. The campaign will include cognitive screening, poster exhibition, booth exhibition and individual counselling.

The SUDOKU training program include a 12-week face-to-face training session and a 12-week facilitated self-practice. The face-to-face sessions aim at developing the skills of the participants in solving the SUDOKU using the T-code. The 12-week training program will be evenly divided into three modules of increasing difficulty, with consideration given to the suboptimal cognitive function of the participants with MCI. These modules are developed by the Co-investigator who has rich prior experience in teaching older adults on SUDOKU puzzle.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2020-09-15
• Study First Submitted: 2021-04-16
• Study First Submitted QC: 2021-05-30
• Study First Posted: 2021-06-04
• Primary Completion: 2023-10-31
• Study Completion: 2023-12-31
• Status Verified: 2024-01
• Last Update Submitted: 2024-01-07
• Last Update Posted: 2024-01-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 262

Inclusion Criteria

• People with MCI as defined by a score of 19-26 out of the 30 on the Montreal Cognitive Assessment in the general public and aged 55 or above.

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Exclusion Criteria

• Persons with dementia and communication problems will be excluded.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
24-week SUDOKU Training Programme	24-week SUDOKU Training Programme	The SUDOKU training program include a 12-week face-to-face training session and a 12-week facilitated self-practice. The 12-week (60-minute sessions) training program will be evenly divided into 3 modules of increasing difficulty for the suboptimal cognitive function of the participants with MCI. As the use of T-code in solving the SUDOKU allows communicating the way a number is assigned to a box, participants are grouped into a small team of 3, so that they will work together during the tutorial practice. Facilitated self-practice will last for another 12 weeks immediately after the group training session. The instructor will give them a workbook with 12 SUDOKU puzzles of increasing level of difficulty for completion. The instructor will encourage and facilitate their accomplishment by giving them guidance on the taught method through regular phone call. Solutions of the assigned puzzle and the T-code will be provided in the following week.
wait-list	Control Arm (wait-list)	wait-list comparison group will receive the same program upon completion of the 6-month posttest evaluation on study outcomes

Primary Outcome Measures

Name	Time	Method
Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)	24-week	To evaluate various domains of cognition
Trail-Making Test Part A and B	24-week	To measure complex attention, executive function and task switching
The digit span-forward and backward test	24-week	To measure attention and working memory
The list learning delayed recall test	24-week	To measure episodic memory

Secondary Outcome Measures

Name	Time	Method
Memory Inventory for Chinese	24-week	To evaluate the subjective memory impairment
The 36-item Chinese version of the Short Form 36 (SF-36)	24-week	To measure Health-related quality of life in the participants

Trial Locations

Locations (1)

Department of Medicine and Geriatrics, United Christian Hospital; 🇭🇰 Hong Kong, Hong Kong