Cognitive interventions in early dementia
Phase 2
- Conditions
- Health Condition 1: G300- Alzheimers disease with early onset
- Registration Number
- CTRI/2023/06/053884
- Lead Sponsor
- Indian Council of Medical Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients satisfying the DSM-IV-TR along with Peterson criteria for MCI or NIAA criteria for early AD as assessed by the clinician
2) Patients with satisfying performance in the psychological tests (MMSE, RAVLT and other tests), administered and evaluated by psychologist.
3) Educated at least up to grade 10th grade
4) Age group of 55-85 years
5) Malayalam speaking
Exclusion Criteria
Patients with metallic implants/pacemakers, neurosurgical history, neuropsychiatric symptoms, claustrophobia, substance abuse, medical conditions that contraindicate performance of MRI
Clinical dementia rating scale > 2.5
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MCI conversion to dementia <br/ ><br>Progression of clinical dementia rating scale (CDR) & IADL scores in early dementiaTimepoint: Sessions weekly for 8 weeks followed by followup neuropsychology assessment at 3 months 1 year followup MRI at 1 year
- Secondary Outcome Measures
Name Time Method MRI changesTimepoint: 1 year