NCT00352638已完成3 期
Colorectal Cancer Screening Intervention for Family Members of Colorectal Cancer Patients
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 660
- 试验地点
- 18
- 主要终点
- Colorectal cancer screening compliance
研究概览
简要总结
RATIONALE: Printed educational materials and counseling by telephone may improve colorectal cancer screening compliance in brothers and sisters of patients with colorectal cancer.
PURPOSE: This randomized phase III trial is studying standard or personalized printed educational materials with or without telephone counseling to compare how well they work in increasing colorectal cancer screening compliance in brothers and sisters of patients with colorectal cancer.
详细描述
OBJECTIVES:
- Compare the impact of 3 interventions (generic educational print intervention, tailored educational print intervention, or tailored educational print intervention plus telephone counseling) on colorectal cancer screening behaviors and intentions among siblings at increased familial risk for colorectal cancer.
Secondary
- Determine whether demographic factors, medical access, physician recommendation at baseline, and proband (patient) characteristics (e.g., stage of disease) moderate the impact of the interventions on colorectal screening.
- Evaluate whether knowledge, attitude, and physician recommendation variables mediate the association between the interventions and colorectal screening, and determine whether these variables are impacted by the interventions.
- Analyze the cost of each intervention.
OUTLINE: This is a randomized, controlled, cohort, multicenter study. Participants are stratified according to study site. Participants are randomized to 1 of 3 intervention arms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •DISEASE CHARACTERISTICS:
- •Sibling of a patient diagnosed with adenocarcinoma of the colon or rectum
- •Patient (proband) must meet the following criteria:
- •Diagnosed in 1999 or later
- •Currently living
- •Seen in Community Clinical Oncology Program member hospital
- •60 and under at diagnosis
- •No history of hereditary cancer syndrome (e.g., familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer) (patient and sibling)
- •No history of colorectal cancer or colorectal polyps (sibling)
- •No history of inflammatory bowel disease (patient and sibling)
- •PATIENT CHARACTERISTICS:
- •Age 40 and over OR within 10 years of proband's (patient's) age at diagnosis
- •English speaking
- •PRIOR CONCURRENT THERAPY:
- •No prior colorectal cancer screening
- •May have undergone prior screening provided they have not followed, or do not plan to follow, physician's recommendation for screening
排除标准
- 未提供
结局指标
主要结局
Colorectal cancer screening compliance
次要结局
- Impact on movement in stage of adoption
- Increased knowledge and attitudes
- Cost
研究者
研究点 (18)
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