A research of efficacy and safety of oxytocin treatment in children and adolescents with reactive attachment disorder using functional magnetic resonance imaging (fMRI).
- Conditions
- Reactive Attachment Disorder
- Registration Number
- JPRN-UMIN000013215
- Lead Sponsor
- niversity of Fukui, Research Center for Child Mental Development, Division of Psychosocial Support for Nurturing
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 55
Not provided
1) History of allergy for oxytocin. 2) Subjects who have any other current DSM-IV-TR diagnosis of the following; "Pervasive development disorder", "Attention-deficit/hyperactivity disorder","Schizophrenia and Other Psychotic Disorders","Delirium, Dementia, and Amnestic and Other Cognitive Disorders", "Substance-Related Disorders","eating disorders","personality disorders". 3) Subjects who have a physical disorder with a need of strict diet, or a diagnosis of a severe physical disorder. 4) Women who are breastfeeding, pregnant, possibility of pregnancy, or have a wish of early pregnancy. 5) Subjects who are planned for an immediate therapeutic plan change due to unstable physical or psychological symptoms. 6) Subjects with metalic device in their body. 7) Subjects who, in the Investigator's opinion, might not be suitable for the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fMRI analysis : Comparison of brain activity change after oxytocin or placebo administration.
- Secondary Outcome Measures
Name Time Method plasma oxytocin concentration oxytocin receptor gene polymorphism neuropsychological test