Supplementation effect of green coffee bean extract on lipid profile, inflammatory and oxidative stress biomarkers, insulin resistance and liver enzymes in overweight and obese patients with nonalcoholic fatty liver disease(NAFLD).

Vice Chancellor for research of Ahvaz Jundishapur University of Medical Sciences0 个研究点目标入组 44 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Men or women aged between 20 to 70 years old who will be diagnosed with NAFLD by ultrasonography scan (with steatosis score equal or greater than 1) and increased levels of liver enzymes (serum levels of alanine aminotransferase and aspartate aminotransferase more than 40 U/L); and Body Mass Index (BMI) of them is grater than 24.9 and lower than 35.
•Exclusion criteria: Alcohol consumption; Pregnant and lactating women; Any known forms of hepatic or metabolic disease except NAFLD, such as hereditary hemochromatosis, Wilson’s disease, cirosis, diabetes and other metabolic disease; Any history of gastric bypass or intestine surgery; Taking hepatotoxic drugs such as calcium channel blocker, methotrexate, amiodarone, chloroquine and anti inflammatory drugs; Using nutrition supplements; Hormone Therapy; and Patients with a history of hypothyroidism, Cushing’s syndrome, renal failure, and kidney stones.

发起方

Vice Chancellor for research of Ahvaz Jundishapur University of Medical Sciences