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Feasability and Clinical Impact Study of Non Pharmacological Interventions in Management of Chronic Pain

Not Applicable
Completed
Conditions
Adapted Physical Activity
Chronic Pain
Slackline
Mindfulness
Self-hypnosis
Qi Gong
Interventions
Other: a systematic proposal for non pharmacological interventions targeting the subject's empowerment among slackline, mindfulness, adapted physical activity, self-hypnosis, and Qi Gong
Registration Number
NCT04176341
Lead Sponsor
University Hospital, Grenoble
Brief Summary

This feasability study aims to compare the 6-month success rate of a systematic proposal for non pharmacological interventions targeting the subject's empowerment among slackline, mindfulness, adapted physical activity, self-hypnosis, and Qi Gong versus usual care in the management of chronic pain.

Detailed Description

Chronic pain management is complex. 27.2 to 43.5 % of general population suffers from it. Opoid crisis has shown the limit of the WHO 3 step analgesic ladder. Multidisciplinary pain management programs, shared decision making and non pharmacological interventions targeting subject's empowerment are needed. Among these non pharmacological interventions, patients are increasingly turning to traditional and complementary medicines. Evidence about their safety and efficacy is hard to build. Thus our study aims to assess the feasibility of a systematic proposal for non pharmacological interventions targeting the subject's empowerment.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
154
Inclusion Criteria
  • Patient with stable chronic pain defined by the presence of pain for more than 3 months and without substantial change in management in the month prior to inclusion
  • Patient with a mean EVA maximum daily pain over 7 days greater than or equal to 4/10
  • Patient aged 18 and over
  • Informed and written consent signed by the patient (or his / her legal representative).
  • Person affiliated with social security or beneficiary of such a scheme
Exclusion Criteria
  • Patient with a cluster headache
  • Patient followed for 7 years or more by a pain center
  • Patient treated with adjuvant or neo-adjuvant chemotherapy or radiotherapy for the primary tumor
  • Patient with a decompensated psychiatric condition
  • Patient currently participating or having participated in the month prior to inclusion in another interventional clinical research that may impact the study; this impact is left to the investigator's discretion
  • Protected persons

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Intervention groupa systematic proposal for non pharmacological interventions targeting the subject's empowerment among slackline, mindfulness, adapted physical activity, self-hypnosis, and Qi Gongchronic pain patient consulting in Grenoble Alps University Hospital, and Hospital Mutualist Group who will one non pharmacological intervention between slackline, mindfulness, adapted physical activity, self-hypnosis, Qi Gong during 6 to 8 weeks.
Primary Outcome Measures
NameTimeMethod
Compare the 6-month success rate of a systematic proposal for non pharmacological interventions targeting the subject's empowerment versus usual care in the management of chronic pain6 months

The success of the intervention will be defined as a reduction of 30% or more of the average daily Visual Analog Score \[0-10\] for pain collected the 7 days prior to the M6 visit, compared to baseline status before intervention.

Secondary Outcome Measures
NameTimeMethod
Evaluate the evolution of the overall motivation of the subjects of the Intervention group at different times of the study: before, during, just after the intervention, and at 3 and 6 months.3 and 6 months

Evaluate the evolution of the overall motivation (EMG-28 scale) at 3 and 6 months compared to baseline for the subjects of the Intervention group.

To evaluate the motivation of the subjects of the intervention group with Likert scales (importance / confidence / disposition) before, during, just after the intervention, and at 3 and 6 months.

Compare the evolution of the ability to cope with subjects at 3 and 6 months compared to baseline.3 and 6 months

Evolution of the Ways of Coping Checklist on the patient's ability to cope at 3 and 6 months compared to baseline

Compare the evolution of the catastrophism of the subjects at 3 and 6 months compared to baseline.3 and 6 months

Evolution of the PCS-CF Pain Catastrophism Scale \[0-52\] at 3 and 6 Months compared to baseline

Describe adherence of the intervention6 months

Number of participated workshops by patients

Compare the effectiveness of the intervention versus usual care between M6-M3-M03 and 6 months

Average daily pain visual analogue scale collected the 7 days prior to the visit of M0, M3 and M6.

We will perform a subgroup analysis per workshop if n ≥ 25 in this one.

Describe side effects of the intervention6 months

Report eventuels side effects occuring during interventions

Compare the evolution of the health care consumption of the subjects at 3 and 6 months compared to baseline.3 and 6 months

Count drug consumption, herbal medicine, homeopathy, food supplements, use of care (medical consultations, hospitalization, use of complementary medicines (acupuncture, osteopathy, micro physiotherapy, chiropractic ...), professional absenteeis that occurs to patient during the study.

Compare changes in quality of life at 3 and 6 months compared to baseline.3 and 6 months

Evolution of the generic quality of life measured by the EQ5D-3L questionnaire at 3 and 6 months compared to baseline

Evaluate the evolution of the detailed motivation of the subjects of the Intervention group at different times of the study: before, during, just after the intervention, and at 3 and 6 months.3 and 6 months

Evaluate motivation of the subjects of the intervention group with Likert scales (importance / confidence / disposition) before, during, just after the intervention, and at 3 and 6 months.

Evaluate the success of the intervention (intervention group) or the conventional follow-up (control group) from the patient's point of view at 3 and 6 months compared to baseline.3 and 6 months

Binary success / failure criterion chosen by the patient during the inclusion visit among 5 criteria previously defined by a focus group of chronic pain patients upstream of the study, at 3 and 6 months compared to baseline.

Sub-group analysis for healthcare professionals : compare the 6-month success rate of a systematic proposal for non pharmacological interventions targeting the subject's empowerment versus usual care in the management of chronic pain6 months

Sub-group analysis for healthcare professionals of the success of the intervention defined as a reduction of 30% or more of the average daily Visual Analog Score \[0-10\] for pain collected the 7 days prior to the M6 visit, compared to baseline status before intervention.

Trial Locations

Locations (1)

CHU de GRENOBLE ALPES

🇫🇷

Grenoble, France

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