MedPath

Sensitivity of the Home Macular Perimeter (HMP)

Completed
Conditions
Age Related Macular Degeneration
Choroidal Neovascularization
Registration Number
NCT00604071
Lead Sponsor
Notal Vision Ltd.
Brief Summary

estimate the sensitivity of the HMP test in identifying visual field functional defects in subjects with CNV secondary to AMD

Detailed Description

The HMP device is intended to aid patients in identifying their visual abnormalities and in addition to their own symptoms or Amsler grid use and aid in their prompt referral to eye care professional examination so clinical diagnosis can be made. As such the goal of the clinical plan is to demonstrate that patients who have CNV do demonstrate visual field abnormalities when tested with the HMP

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
99
Inclusion Criteria
  • Capable and willing to sign a consent form and participate in the study
  • subjects with AMD related lesions: New onset (up to 60 days) non-treated CNV
  • Age >50 years
  • VA with habitual correction >20/200 in study eye
  • Familiar with computer usage
Exclusion Criteria
  • Evidence of macular disease other than AMD or glaucoma in the study eye
  • Presence of any significant media opacity that precludes a clear view of the macular area as identified in the study eye by biomicroscopy, CFP, or FA
  • Any non-macular related ocular surgery performed within 3 months prior to study entry in the targeted eye
  • Inability to tolerate intravenous FA
  • Participation in another study with the exclusion of AREDS study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
estimate the sensitivity of the HMP test in identifying visual field functional defects in subjects with CNV secondary to AMD based on PRC grading of color stereo photographs and Stereoscopic fluorescein angiogram3 month
Secondary Outcome Measures
NameTimeMethod
Estimate the sensitivity of the HMP in identifying visual field functional defects in subjects with CNV secondary to AMD based on cases where both graders, prior to any adjudication process, and biomicroscopic finding determined the presence of CNV3 Month
Estimate the sensitivity of the HMP in identifying visual field functional defects in subjects with CNV secondary to AMD determined on biomicroscopy3 month
Estimate the sensitivity of the Amsler grid test in identifying functional changes in subjects with CNV secondary to AMD based on PRC grading of color stereo photographs and fluorescein angiograms.3 month
Estimate the sensitivity of the HMP in identifying visual field functional defects in subjects with CNV secondary to AMD based in cases where both graders, prior to any adjudication process determined the presence of CNV3 month
Estimate the sensitivity of the HMP test in identifying visual field functional defects in subjects with CNV secondary to AMD for each of three classifications of CNV lesions (occult, minimally classic and predominantly classic).3 month
Estimate the sensitivity of the HMP test in identifying visual field functional defects in subjects with CNV secondary to AMD which were either minimally classic or occult and where the physician elected to treatment over observation3 month

Trial Locations

Locations (10)

Charlotte Eye Ear Nose & Throat

🇺🇸

Charlotte, North Carolina, United States

Virginia Retina Center

🇺🇸

Leesburg, Virginia, United States

Edina Retina Consultants

🇺🇸

Edina, Minnesota, United States

International Eye Center

🇺🇸

Tampa, Florida, United States

Retina Vitreous Center

🇺🇸

New Brunswick, New Jersey, United States

Central Florida Retina Institute

🇺🇸

Lakeland, Florida, United States

Center for Retina & Macular Disease

🇺🇸

Winter Haven, Florida, United States

Foxman Foxman & Margolis

🇺🇸

Northfield, New Jersey, United States

Retina care specialists

🇺🇸

Palm Beach Gardens, Florida, United States

Harkness Eye institute

🇺🇸

W. New York, New Jersey, United States

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