Old Blood and Postoperative Complications

Withdrawn

• Conditions: Orthopedics; Red Blood Cells; Postoperative Complications
• Interventions: Procedure: New red blood cells transfusion; Procedure: Old red blood cells transfusion

• Registration Number: NCT02575820
• Lead Sponsor: Seoul National University Hospital

Brief Summary

The investigators sought to examine the effects of 'old' red blood cells on mortality and morbidity of patients who undergoing revision hip replacement arthroplasty. The investigators hypothesis is that patients have an increased risk of mortality and infection after 'old' red blood cells transfusions compared with those who received 'new' transfusions.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-10-11
• Study First Submitted QC: 2015-10-14
• Study First Posted: 2015-10-15
• Study Start: 2015-11
• Status Verified: 2016-05
• Primary Completion: 2016-05
• Study Completion: 2016-05
• Last Update Submitted: 2016-05-12
• Last Update Posted: 2016-05-13

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients who underwent revision total hip replacement

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Exclusion Criteria

• Patients who were not given red blood cells
• Patients who were given two units of which one unit was old and one was new

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
RBC_new	New red blood cells transfusion	shelf life of red blood cells 14 or lower days
RBC_old	Old red blood cells transfusion	shelf life of red blood cells of 15 or higher days

Primary Outcome Measures

Name	Time	Method
Wound infection	postoperative 7 days
Mortality	postoperative 7 days
Sepsis	postoperative 7 days
Postoperative delirium	postoperative 7 days
Postoperative bleeding	postoperative 7 days

Secondary Outcome Measures

Name	Time	Method
Transfusion related lung injury	postoperative 7 days
Pulmonary edema	postoperative 7 days
Pulmonary effusion	postoperative 7 days
Myocardial ischemia	postoperative 7 days
Pulmonary thromboembolism	postoperative 7 days
Renal failure	postoperative 7 days
Hepatic failure	postoperative 7 days

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seongnamsi, Korea, Republic of