Intrauterine Misoprostol With Active Management of Labour Versus Active Management of Labour for Prevebtion of Postpartum Hemorage in Cesarean Section ,Randomized Controlled Trial
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- The number of participants who passed cesarean section without postpartum hemorage
研究概览
简要总结
Several treatment strategies are emplemented to prevent post delivery hemorage and decreasing maternal morbidity and mortality .
详细描述
Many approved drugs are used in prophylaxis against postpartum hemorage from these medications are the (syntocinon combined with methergine ) that are known as active management of labour drugs .
Moreover there is misotac , that also guards against postpartum hemorage .
All these medications act in a different way to cause uterine contraction post delivery to prevent uterine atony .
-Here we are comparing the additive value of misotac intrauterine to syntocinon and methergine in comparison to the usually used syntocinon plus methergine .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 42 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •• All patients included in this research were aged 18-42 years, pregnant 37 weeks till 42 weeks
- •no medical disorders with pregnancy e.g DM, HTN. All patients were subjected to full history taking, examination.
排除标准
- •Exclusion Criteria:
- •The following patients were excluded , GA before 37 weeks or after 42 weeks , medical disorders with pregnancy eg. DM with pregnancy, HTN with pregnancy
研究组 & 干预措施
Extra medication group
-Procedure : Giving misoprostol plus syntocinon during CS
this group in which prevention of uterine atony is made by intrauterine misoprostol plus the usual syntocinon and using extra uterotonic drugs when needed ; methergine , carboprost
干预措施: Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergine (Drug)
Active management of labour group
- Procedure: Giving syntocinon during cesarean section
- this group in which prevention of uterine atony is made by the usual active management of labour syntocinon and using extra uterotonic drugs when needed ; methergine , carboprost
干预措施: Syntocinon and using extra uterotonic drugs when needed ; methergine carboprost (Drug)
结局指标
主要结局
The number of participants who passed cesarean section without postpartum hemorage
时间窗: within 2 days post CS
次要结局
未报告次要终点