Comparison between two different antiemetic regimens in patients treated with concurrent chemoradiotherapy for locally advanced head and neck squamous cell cancer : A Randomized, Double Blind, Controlled Clinical Trial
Phase 4
Not yet recruiting
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/06/068878
- Lead Sponsor
- Pt BD Sharma UHS Rohtak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Histologically confirmed cases of squamous cell carcinoma in head & neck region with any stage between Stages III-IV B.
Patients with ECOG performance status 0–1
Patients with adequate organ and bone marrow function.
Patient is able to swallow tablets
Exclusion Criteria
•advanced stage malignancies(above Stage IVB)
•History of nausea and emesis occurred 24h before the start of CCRT.
•Conditions like severe cardiovascular, pulmonary, diabetic, mental, and other diseases.
•Pregnant or lactating females.
•Drug h/o corticosteroid or benzodiazepines.
•History of Drug/Alcohol addictions.
•N&V provoking conditions like brain metastasis, gastrointestinal obstruction, hypocalcemia;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method