Evaluating the role of graduated compression stockings in the prevention of blood clots in patients who undergo short-stay surgery and who are assessed as being low-risk of developing blood clots

Not Applicable

• Conditions: Prevention of venous thromboembolism (VTE) in patients who are deemed to be at low-risk of developing VTE and who undergo day-case/short-stay surgical procedures.; Circulatory System

• Registration Number: ISRCTN13908683
• Lead Sponsor: Imperial College London

Brief Summary

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36653057/ (added 19/01/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-03-29
• Last Update Posted: 28 August 2023
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 21472

Inclusion Criteria

1. Adults (18-59 years of age) scheduled to undergo a surgical procedure with a hospital stay <48 hours
2. Individuals assessed as being at low-risk of developing VTE as per the DHRA tool i.e. no assessed thrombosis risk factors / scoring 0

Exclusion Criteria

Current exclusion criteria as of 14/08/2023:
1. Individuals with a contraindication to GCS
2. Individuals assessed as being at moderate or high-risk of VTE as per the DHRA tool
3. Individuals requiring therapeutic anticoagulation
4. Individuals with thrombophilia/ thrombogenic disorder
5. Individuals with a previous history of VTE
6. Individuals requiring intermittent pneumatic compression therapy beyond theatre and recovery
7. Individuals requiring extended thromboprophylaxis beyond discharge
8. Female patients of childbearing age who have a positive pregnancy test
9. Individuals with lower limb immobilisation
10. Inability to provide informed consent
11. Individuals requiring pharmacological prophylaxis
_____

Previous exclusion criteria:
1. Individuals with a contraindication to GCS
2. Individuals assessed as being at moderate or high-risk of VTE as per the DHRA tool
3. Individuals requiring therapeutic anticoagulation
4. Individuals with thrombophilia/ thrombogenic disorder
5. Individuals with a previous history of VTE
6. Individuals requiring intermittent pneumatic compression therapy beyond theatre and recovery
7. Individuals requiring extended thromboprophylaxis beyond discharge
8. Female patients of childbearing age who have a positive pregnancy test
9. Individuals with lower limb immobilisation
10. Inability to provide informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified