NCT07313501RecruitingNot Applicable
Evaluation of the PERC Score and the YEARS Algorithm in the Diagnosis of Pulmonary Embolism in the Emergency Department: a Retrospective Observational Study in the Emergency Department of the Strasbourg University Hospital
University Hospital, Strasbourg, France1 site in 1 country500 target enrollmentStarted: February 26, 2025Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Number of patients who would not have required imaging if the PERC score and YEARS algorithm criteria had been applied
Study Overview
Brief Summary
The current diagnostic strategy for pulmonary embolism relies on clinical evaluation, followed by D-dimer testing and chest CT angiography. However, this approach leads to overuse of CT angiography. Diagnosis remains complex, with nonspecific clinical signs. Recent studies have explored new algorithms, such as the YEARS algorithm and the PERC score, which aim to support the diagnosis and reduce the need for imaging examinations. Their use could decrease waiting times in the emergency department and limit the need for additional investigations.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adult patient (≥18 years)
- •Patient admitted to the adult emergency department of the Strasbourg University Hospital over a 6-month period (January to June 2024), for whom a D-dimer test and chest imaging (thoracic CT angiography or ventilation/perfusion scintigraphy) were performed
Exclusion Criteria
- •- No D-dimer test or test performed for another indication, no chest imaging (CT angiography or scintigraphy), long-term anticoagulant treatment.
Outcomes
Primary Outcomes
Number of patients who would not have required imaging if the PERC score and YEARS algorithm criteria had been applied
Time Frame: Up to 12 months
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Recruiting
Phase 2
Development of dynamic X-ray inspection technologyPulmonary embolismJPRN-jRCTs032220118Miyatake Kazuma444
Not yet recruiting
Not Applicable
Can this scoring system predict death in pulmonary embolismCTRI/2021/04/033111Dept Of Emergency Medicine
Completed
Phase 4
Age-adjusted D-dimer Cut-off Levels to Rule Out Pulmonary EmbolismPulmonary EmbolismNCT01134068Marc Righini3,306
Recruiting
Not Applicable
Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and EffectivenessNCT07280247Angiodynamics, Inc.39
Completed
Not Applicable
PERC Rule to Exclude Pulmonary Embolism in the Emergency DeparmentEmergency PatientsNCT02375919Assistance Publique - Hôpitaux de Paris1,922