ACTRN12621000815864招募中未知
Does therapeutic plasma exchange improve outcomes in severe Guillain-Barre Syndrome (GBS) compared to intravenous immunoglobulin? A protocol for a New Zealand pilot study
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1)A diagnosis of GBS by Cornblath and Asbury criteria .
- •2)GBS severity of 4 or 5 by Hughes GBS severity scale OR early treatment outcome (EGOS) score of 5 or greater OR early GBS respiratory insufficiency (EGRIS) score of 5 or greater.
- •3)Able to start assigned treatment within 2 weeks of weakness onset.
- •4)At least 18 years of age at the time of enrollment.
- •5)Able to provide informed consent
排除标准
- •1) Any antecedent illness that would interfere with the ability to perform outcome assessments
- •2)History of an allergy to IVIg
- •3)History of an allergic reaction to Albumin 4%.
- •4)History of IgA deficiency with anti-IgA antibodies
- •5)Known reaction to blood products
- •6)Patient with strong objection to the use of blood products
研究者
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