Impact of Aerobic Physical Training Associated With Noninvasive Ventilation on COPD Patient Functionality - A Controlled Randomized Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
- Sponsor
- Universidade Federal de Sao Carlos
- Enrollment
- 23
- Locations
- 1
- Primary Endpoint
- Impact of aerobic exercise, either associated or not with NIV, by two positive pressure levels on COPD patient functionality.
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
On the following tests, there would be a greater increase in the functionality of COPD patients who underwent combined therapy than in those who only exercised: a set of activities of daily living (ADLs), the six-minute walk test (6MWT), an incremental symptom-limited cardiopulmonary test (CPT), and the physical functioning scale of the Short-Form 36 quality of life questionnaire (SF-36).
Detailed Description
Impact of aerobic exercise plus noninvasive ventilation (NIV) on the functionality of patients with COPD. Thirty patients (70.5 - 8.5 years) with COPD (forced expiratory volume in the first second 48.5 - 15.4% of predicted) were randomized into either a physical training group involving aerobic treadmill exercise (PTG, n=12) or an exercise plus bilevel ventilation group (PTGNIV, n=11) with sessions three times a week for six weeks.
Investigators
Kamilla Tays Marrara
Doutoranda em Fisioterapia pela Universidade Federal de São Carlos - UFSCar.
Universidade Federal de Sao Carlos
Eligibility Criteria
Inclusion Criteria
- •COPD diagnosis
- •with a forced expiratory volume in the first second (FEV1)/forced vital capacity (FVC)\<70%
- •clinical stability in the previous two months (i.e., no exacerbation of the disease).
Exclusion Criteria
- •decompensated heart failure or rheumatic, orthopedic or neuromuscular diseases that prevented the subjects from performing the tests due to exercise limitations;
- •participation in a regular physical exercise program at the beginning of the study;
- •noncompletion of one of the tests or the established protocol for any reason.
Outcomes
Primary Outcomes
Impact of aerobic exercise, either associated or not with NIV, by two positive pressure levels on COPD patient functionality.
Time Frame: 6 weeks
It was measured by means of step-climbing repetitions and distance covered in the six-minute walk test as well as the CPT.
Secondary Outcomes
- Change in oxygen consumption.(6 weeks)
- Change in metabolic rate.(6 weeks.)
- Change in oxygenation.(6 weeks.)
- Change in sensation of dyspnea.(6 weeks)
- Change in quality of life.(6 weeks.)