Vascular function in obesity

Not Applicable

• Conditions: Cardiovascular disease associated with obesity; Circulatory System; Cardiovascular disease

• Registration Number: ISRCTN15446376
• Lead Sponsor: The University of Manchester

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-04-29
• Last Update Posted: 20 July 2020
• Study Completion: 2020-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patient-participants:
1. Willing and capable to provide consent to participation
2. BMI greater than 30
3. No known ocular diseases
4. No known concurrent clinical problem likely to interfere with participation or completion of the study

Healthy controls:
1. BMI lower that 25
2. No known diabetes
3. No known ocular diseases
4. No known concurrent clinical problem likely to interfere with participation or completion of the study

Exclusion Criteria

1. Under 18 years old
2. Intubated/ventilated patients
3. Unwilling to give consent to participation OR advised by consultee that this would be against the patient’s wishes
4. Smoker
5. If eaten with in an hour of the examination
6. If drank alcohol within an hour of the examination
7. If drank coffee within an hour of the examination
8. If overly hungry
9. Recently treated infection
10. Known ocular diseases
11. Known concurrent clinical problem likely to interfere with participation or completion of the study

Additional exclusion for healthy controls:
1. Diabetes
2. BMI above 25

Study & Design

• Study Type: Observational
• Study Design: Not specified