Real-World Effectiveness and Safety of Dabigatran in Geriatric Patients with Atrial Fibrillatio
- Conditions
- Dabigatran was used to prevent ischemic stroke in atrial fibrillation but effectiveness and safety are diferent between geriatric patients and young patients.dabigatran, non-vitamin k antagonist oral anticoagulants, NOAC, direct oral anticoagulant, DOAC, geriatric, elderly, atrial fibrillation, ischemic stroke, bleeding
- Registration Number
- TCTR20221222001
- Lead Sponsor
- Faculty of Pharmacy, Silpakorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- nknown
- Sex
- All
- Target Recruitment
- 2134
Inclusion Criteria
Thai patient who was more than twenty years old and got dabigatran 150 milligrams, 110 milligrams or 75 milligrams twice daily for non-valvular atrial fibrillation indication.
Exclusion Criteria
- Patient with mechanical valve replacement or moderate to severe mitral stenosis.
- ESRD patient or eGFR less than 15 ml/min.
- Pregnancy or lactation patient.
- Incomplete patient data.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ischemic stroke since 3 months, not more than 2 years after patient got dabigatran Retrospective data record since 1/1/2011 until 31/7/2022 from OPD card, IPD card and eletronic card,Bleeding since 3 months, not more than 2 years after patient got dabigatran Retrospective data record since 1/1/2011 until 31/7/2022 from OPD card, IPD card and eletronic card
- Secondary Outcome Measures
Name Time Method Risk factor of ischemic stroke in geriatric patients since 3 months, not more than 2 years after patient got dabigatran Retrospective data record since 1/1/2011 until 31/7/2022 from OPD card, IPD card and eletronic card,Risk factor of bleeding in geriatric patients since 3 months, not more than 2 years after patient got dabigatran Retrospective data record since 1/1/2011 until 31/7/2022 from OPD card, IPD card and eletronic card