a clinical trial to find the most appropriate maintenance fluid in children with central nervous system infectio
Phase 3
Completed
- Conditions
- Health Condition 1: null- to compare the incidence of hyponatremia with maintenance fluids ( isotonic and hypotonic) in children with CNS infections
- Registration Number
- CTRI/2012/05/002637
- Lead Sponsor
- Kalawati Saran Chiuldrens Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
children of age 2month to 5 years with a clinical diagonosis of CNS infections requiring maintenance fluids for atleast 24 hrs
Exclusion Criteria
-serum sodium less than 135 or more than 145 mmol/ L before starting maintenance fluids
- previously diagonosed renal disease
-documented cerebral salt wasting
-hepatic failure with fluid retention
-shock at presentation
-diarrhoea
-known endocrinal disorder(DI/IDDM/CAH)
-severe malnutrition(asTBW in malnourished children is 70-80%as compared to 60% age matched well nourished controls)
-DKA/cranioenchephalic trauma (at risk of cerebral edema)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method