临床试验/NCT07149805

NCT07149805已完成不适用

Surgery Improves Survival Rate in Patients With Takayasu Arteritis: a Retrospective Observational Study

Peking Union Medical College Hospital0 个研究点目标入组 78 人开始时间: 2004年1月1日最近更新: 2025年9月2日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Peking Union Medical College Hospital
入组人数: 78
主要终点: all-cause mortality rate

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

The long-term prognosis and optimal management for Takayasu arteritis(TA) patients with severe stenosis of the descending thoracic and abdominal aorta remain undefined. We want to compare the clinical outcomes of surgical intervention and medical management.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•fulfilling the 1990 American College of Rheumatology criteria for the diagnosis of TA;
•having at least one site with severe narrowing in the descending thoracic and abdominal aorta;
•having symptoms caused by TA-related stenosis, such as uncontrolled hypertension, heart failure, renal ischemia, dizziness, visual disturbances, and claudication

排除标准

•Patients with arterial stenosis due to other reasons (such as typical atherosclerosis, congenital coarctation of the aorta, and anatomical abnormality) were excluded

结局指标

主要结局

all-cause mortality rate

时间窗: Patients underwent follow-up from discharge (3 years to 11 years) until study termination or death, whichever came first

次要结局

未报告次要终点

研究者

发起方

Peking Union Medical College Hospital

申办方类型

Other

责任方

Principal Investigator

主要研究者

Yuexin Chen

professor

Peking Union Medical College Hospital

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