Comparative effect of Melatonin, Gabapentin and Dexmedetomidine on post-operative pain and anxiety in patients undergoing laminectomy

Phase 2

Recruiting

• Conditions: laminectomy.; M53.2X6; Spinal instabilities, lumbar region

• Registration Number: IRCT20141009019470N82
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 99

Inclusion Criteria

Age between 30 and years
ASA class I and II
One or two levels of lumbar laminectomy ± discectomy

Exclusion Criteria

Sensitivity to each of medications
Heart disease
Liver disease
Psychological and cognitive disabilities
Known cases of chronic pain syndromes
Drug abuse
Neurological disease
Circadian rhythm disruption (such as daytime fatigue , somnolence)
Renal disease
Opium addicted patients

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of pain. Timepoint: 2-hour, 6-hour and 24-hour after surgery. Method of measurement: VAS Score.;Anxiety. Timepoint: 2-hour, 6-hour and 24-hour after surgery. Method of measurement: HADS questionnaire.

Secondary Outcome Measures

Name	Time	Method
Patients Satisfaction. Timepoint: 24 Hours after surgery. Method of measurement: Likert Scale.