BREATHE: Building Respiratory Support in East Africa Through High Flow versus Standard Flow Oxygen Evaluatio

Not Applicable

Not yet recruiting

• Conditions: Any form of hypoxemia; Respiratory

• Registration Number: PACTR202306684141777
• Lead Sponsor: Beth Israel Deaconess Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-31
• Last Update Posted: 2024-03-04

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 424

Inclusion Criteria

age 18 years and above AND
- admitted to a study site hospital within the 24 hours prior to screening AND
- SpO2 less than 90% at time of first assessment OR
- receiving oxygen at time of first assessment

Exclusion Criteria

-imminent death (high clinical suspicion of death within 24 hours of admission)
- patient or caregiver refusal of study participation
- history of chronic respiratory failure (chronic SpO2 less than 90%) or chronic oxygen dependence for at least 3 months
- anatomical factors precluding the use of nasal cannula
- intubation or non-invasive ventilation by the clinical team prior to screening for the trial
- known hypoxemia at transferring facility for more than 48 hours
- lack of availability of either SFO or HFO devices or supplies at the time of randomization.

Study & Design

• Study Type: Interventional
• Study Design: Not specified