Efficacy and overall impact on wound healing of acetic acid and ascorbic acid as antiseptics in chronic diabetic wounds
Not Applicable
- Conditions
- Chronic diabetic wounds
- Registration Number
- SLCTR/2014/035
- Lead Sponsor
- Department of Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
1.Age over 18 years
2.Chronic diabetic wounds which have lasted over 1 month
3.No clinical evidence of occlusive arterial disease
Exclusion Criteria
1. Uncontrolled diabetes needing inward management
2. Clinical evidence of concurrent occlusive arterial disease (OAD).
3. Other co-morbidities requiring use of systemic antibiotics
4. Any patient needing surgical intervention or use of other methods (rotational antiseptics) to control wound infection. I
5. Known hypersensitivity to acetic acid or ascorbic acid
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Wound healing according to PEDIS score (Perfusion, Extent/size, Depth/tissue loss, Infection, and Sensation) and an objective wound assessment questionnaire [At baseline, at the end of one week and at the end of 1 month]<br>
- Secondary Outcome Measures
Name Time Method 1. Bacterial colony count of the wound<br>2. pH of the wound<br> [Both secondary outcomes will be assessed at the following time points.<br><br>Day 1: Pre swab (prior to antiseptic instillation), 10 minutes after instillation, 1 hour after instillation, 4 hours after instillation<br><br>Day 3: Pre swab (prior to antiseptic instillation), 10 minutes after instillation, 1 hour after instillation, 4 hours after instillation<br><br>At the end of one month<br>]<br>