Retinal blood vessel changes in eyes of Glaucoma patients with and without Diabetes

Not Applicable

• Conditions: Health Condition 1: H401- Open-angle glaucomaHealth Condition 2: E11- Type 2 diabetes mellitusHealth Condition 3: H579- Unspecified disorder of eye and adnexa

• Registration Number: CTRI/2020/12/029846
• Lead Sponsor: Aravind Eye Hospital Pondicherry

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

• Best corrected visual acuity of 6/12 or better, with spherical refractive error

between â?? 3 diopter to + 3 diopter and a cylindrical correction within 3 diopter

• Normal anterior chamber depth and open angles

• No history of intraocular surgery, except cataract surgery after the 1 st post-

operative month

• Willing to give written informed consent

The participants will be included into one of these four groups:

CASES (Patients with Glaucoma)

Group 1 â?? Glaucoma and no diabetes

Newly diagnosed and review patients of POAG and NTG without any history of

systemic illness and no clinically detectable fundus pathology other than

glaucoma.

Group 2 â?? Glaucoma and Diabetes

Newly diagnosed and the patients presenting for review visits with POAG or

NTG, with type 2 diabetes mellitus of any duration, without any other systemic

illness and having no clinically visible diabetic retinopathy changes.

CONTROLS (Patients without glaucoma)

Group 3 â?? Controls without diabetes

1. Individuals with no history or evidence of any retinal and eye pathology.

2. Individuals with no optic disc damage clinically and no history of any systemic

or neurological diseases capable of causing visual field loss or optic disc

deterioration.

3. IOP <= 21 mmHg measured on applanation tonometry

4. Open Angles

Group 4 â?? Controls with Diabetes

1. New or review patients with history of type 2 diabetes mellitus of any duration

having no clinically visible diabetic retinopathy changes.

2. IOP <= 21 mmHg measured on applanation tonometry.

3. Open Angles

Exclusion Criteria

Patients with any media opacity including corneal opacity, cataract greater than

nuclear cataract of grade NO3 and NC3, Cortical cataract of grade C3 and

Posterior subcapsular cataract of grade P3 as per Lens Opacification

Classification System III 8

• Any retinal or macular pathology.

• Systemic illness other than type 2 diabetes mellitus

Study & Design

• Study Type: Observational
• Study Design: Not specified