Prospective study of predictors of the diagnosis of delirium or future development of the delirium: the association between serum anticholinergic levels and dignosis or future development of delirium in palliative care patients with advanced cancer.

Not Applicable

Completed

• Conditions: Delirium in advanced cancer; Cancer -

• Registration Number: ACTRN12606000182594
• Lead Sponsor: Sacred Heart palliative care services and Flinders University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-05-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

i.Admission to a palliative care inpatient unit.ii.male and female patients with Advanced cancer.iii.Predicted survival of greater than 7 days.

Exclusion Criteria

i.Non-English speaking background.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Association of Serum Anticholinergic Levels (SAL) on admission to palliative care unit and at delirium occurrence with admission diagnosis of delirium or future occurrence during admission of delirium[Patients will be followed from admission to palliative care inpatient unit until death or discharge for delirium episdoes.]

Secondary Outcome Measures

Name	Time	Method
i. Association of rating on Clinician rated Anticholinergic Scale – modified version (on admission and daily scores for period of observation) with occurrence of delirium.[on admission, daily];ii.Sensitivity and specificity for SAL (taken on admission and level taken if delirium occurs i.e daily memorial delirium score of 10 or above on daily assessment) for diagnosis of incident and prevalent delirium.[on admission, at delirium];iii.Predictive model of investigational and clinical parameters on admission for incident and prevalent delirium.[on admission, at delirium]