Changhai Hospital, the Second Military Medical University
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,028
- 主要终点
- Numbers of chronic pancreatitis patients with post-ERCP pancreatitis, diabetes mellitus, steatorrhea, previous pancreatitis, previous PEP, pancreatic divisum, jaundice, ESWL, pancreatic duct stone, drainage and minor papilla pancreatogram.
研究概览
简要总结
The purpose of this study is to compare the incidence of post-ERCP pancreatitis (PEP) in chronic pancreatitis (CP) patients to that in biliary disease patients, to determine whether CP patients in early clinical stage have a higher PEP incidence, and to identify the predictive and protective factors for PEP in chronic pancreatitis patients.
详细描述
Analysis of patients with chronic pancreatitis (CP group) and biliary disease (BD group) in Changhai Hospital from January 2011 to May 2015 were conducted. Difference of PEP incidences between BD group and CP group, as well as between M-ANNHEIM subcategories were calculated by chi-square test or Fisher's exact test. The predictive and protective factors for PEP were investigated by univariate and multivariate analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
入排标准
- 年龄范围
- 5 Years 至 85 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with an endoscope inserted to cannulate the pancreatic/biliary duct were included.
排除标准
- •patients in whom the papilla of Vater was not reached;
- •patients who underwent stent removal procedures without ductal cannulation;
- •patients in whom the intubation was failed.
结局指标
主要结局
Numbers of chronic pancreatitis patients with post-ERCP pancreatitis, diabetes mellitus, steatorrhea, previous pancreatitis, previous PEP, pancreatic divisum, jaundice, ESWL, pancreatic duct stone, drainage and minor papilla pancreatogram.
时间窗: 8 months
次要结局
- Numbers of biliary disease patients with post-ERCP pancreatitis, previous pancreatitis and previous PEP.(2 months)
研究者
Zhuan Liao
associate professor
Changhai Hospital