Role of individualized homoeopathic medicines in the treatment of Acne vulgaris: Double- blind, randomized, placebo-controlled trial

Recruiting

• Conditions: Acne vulgaris,

• Registration Number: CTRI/2023/12/060827
• Lead Sponsor: Central council for research In Homoeopathy

Brief Summary

Title: "Effectiveness of Individualized Homoeopathic Medicines in the Treatment of Acne Vulgaris: A Double-Blind, Randomized, Placebo-Controlled Trial"



Abstract:



Objective: This double-blind, randomized, placebo-controlled trial aims to investigate the effectiveness of individualized homoeopathic medicines in the treatment of Acne Vulgaris.



Methods: A cohort of 120 individuals diagnosed with Acne Vulgaris will be randomly assigned to either the intervention group receiving individualized homoeopathic medicines or the control group receiving a placebo. The randomization will be performed using computer-generated random numbers. Both groups will be subjected to identical double-blind procedures, ensuring that neither the participants nor the investigators are aware of the treatment allocation.



Intervention: Participants in the intervention group will receive individualized homoeopathic medicines tailored to their specific symptoms and constitution. The selection of homoeopathic remedies will be based on a thorough individualized assessment conducted by experienced homoeopathic practitioners. The control group will receive a placebo with similar appearance and taste.



Outcome Measures: The primary outcome measure will be the reduction in GAGS score (Global Acne Grading system). Secondary outcome measures will include CADI score and photographic improvement.



Keywords: Acne Vulgaris, Homoeopathic Medicines, Individualized Treatment, Double-Blind, Randomized Controlled Trial, Placebo.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-01
• Last Update Posted: 2024-03-10

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Patients willing to give written consent to undergo homoeopathic treatment.
• Age range: 11-40 years.
• Both sexes, all socio-economic status, all religions.
• Those patients who have been diagnosed with acne vulgaris.
• Patient willing to give written consent (Children between 11 to 15 years should give written consent in presence of parents).

Exclusion Criteria

• Patients suffering from life-threatening infections.
• Cases already undergoing homoeopathic treatment elsewhere for other chronic disease.
• Patients having Substance abuse and/ or dependence.
• Patient below 11 years and above 40 years.
• Patient suffering from other underlying deep dyscrasias like PCOS etc.
• which is responsible for Acne vulgaris.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Global Acne Grading Score (GAGS)	Fortnightly till 4month.

Secondary Outcome Measures

Name	Time	Method
Cardiff Acne disability index (CADI)	Fortnightly till 4month.

Trial Locations

Locations (3)

Central Council for Research in Homeopathy.; 🇮🇳 West, DELHI, India

Dr, D P Rastogi Central Research Institute for Homoeopatlhy.; 🇮🇳 Nagar, UTTAR PRADESH, India

Regional Research Institute for Homoeopathy, Shimla; 🇮🇳 Shimla, HIMACHAL PRADESH, India

Central Council for Research in Homeopathy.

🇮🇳West, DELHI, India

Dr Deepti Singh

Principal investigator

9818785593

dr.deepti.2821@gmail.com