Serum Magnesium Level in Type 2 Diabetes Mellitus

Not yet recruiting

• Conditions: Diabetes Mellitus
• Interventions: Diagnostic Test: Magnesium

• Registration Number: NCT06059833
• Lead Sponsor: Sohag University

Brief Summary

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resistance to peripheral actions of insulin, or both . Chronic hyperglycemia in synergy with the other metabolic aberrations in patients with diabetes mellitus can cause damage to various organ systems, leading to the development of disabling and life-threatening health complications, most prominent of which are microvascular (retinopathy, nephropathy, and neuropathy) and macrovascular complications leading to a 2-fold to 4-fold increased risk of cardiovascular diseases Mg2+ deficiency is usually identified by the measurement of serum Mg2+ concentration. Hypomagnesemia is defined by a serum Mg2+ concentration \< 0.75 mmol/L, but a deficiency due to low dietary intake in otherwise healthy people is uncommon. Although overt signs of clinical Mg2+ deficiency are not routinely recognized in the healthy population, relatively low Mg2+ intake and/or Mg2+ status have been shown to be associated with chronic diseases, including cardiovascular disease, T2DM, osteoporosis, pulmonary disease, depression, migraine headaches, inflammation, and cancer

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-09
• Study Start: 2023-09
• Study First Submitted: 2023-09-22
• Study First Submitted QC: 2023-09-22
• Last Update Submitted: 2023-09-22
• Study First Posted: 2023-09-29
• Last Update Posted: 2023-09-29
• Primary Completion: 2024-09
• Study Completion: 2024-09

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

• • Type 2 Diabetes Mellitus according to WHO criteria.

Exclusion Criteria

• • Renal failure patients.

  • Type I DM patients.
  • Acute pancreatitis.
  • Hyperthyroidism.
  • Hyperparathyroidism.
  • Malignancies.
  • Patients on loop/thiazide diuretics.
  • Patients on Mg supplement.
  • Patients on Mg containing antacids.
  • Any other conditions causing low Mg levels were excluded from the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cases group	Magnesium	-
control group	Magnesium	-

Primary Outcome Measures

Name	Time	Method
magnesium perecentage	1 year	evaluate serum Mg level in type 2 DM patients.

Trial Locations

Locations (1)

Sohag university Hospital; 🇪🇬 Sohag, Egypt