Multiinstitutional prospective study on idiopathic interstitial pneumonias with features similar to collagen vascular diseases
Not Applicable
- Conditions
- Idiopathic interstitial pneumonias
- Registration Number
- JPRN-UMIN000010231
- Lead Sponsor
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine
- Brief Summary
In this multicenter cohort study, 376 patients with IIP prospectively enrolled, and 70 patients (18.6%) met the IPAF criteria. During a median observation period of 35 months, patients with IPAF more frequently developed systemic autoimmune diseases and had less frequent acute exacerbation of IIPs than patients with non-IPAF. IPAF diagnosis was significantly associated with better survival and was an independent positive prognostic factor in total and patients with non-IPF.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 376
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who meet the criteria for any collagen vascular diseases
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival rate
- Secondary Outcome Measures
Name Time Method Change in Forced Vital Capacity, Change of lung opacities on High Resolution Computed Tomography