Efficacy and safety of oral soy extract recipe product on anti-skin aging of postmenopausal wome

Phase 2

Completed

• Conditions: Postmenopausal women; Postmenopausal, soy extract, anti-skin aging

• Registration Number: TCTR20220707001
• Lead Sponsor: Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-07
• Study Completion: 2023-04-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 94

Inclusion Criteria

1) Healthy volunteers (based on medical history and physical
examination) and > 1 year postmenopausal, 2) FSH > 30 mU/mL, 3) Body mass index (BMI) 18-30 kg/m2.

Exclusion Criteria

1) Known contraindication or hypersensitivity to soybean and other soya
products, 2) Treatment with estrogens or isoflavone for the previous 6 months, 3) Taking retinoids, vitamin, minerals, herbal substances, antibiotics, steroids, or immunosuppressants within 3 months prior to enrollment, 4) A history of chronic disorders related to renal, liver, cardiovascular, brain, GI, blood or thyroid, 5) Regular consumption of alcohol, cigarette smoking, or recreational drugs use/addiction.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Skin Evaluation at 0 and 12 weeks after end of the intervention Visiometer, Visiopor, Corneometer, Colorimeter, Cutometer

Secondary Outcome Measures

Name	Time	Method
Quality of life at 12 weeks after end of the intervention The MENQOL questionnaire,Vasomotor symptoms at 12 weeks after end of the intervention The Modified Kupperman Index,Bone turnover markers at 12 weeks after end of the intervention Osteocalcin, TotalP1NP and Beta-crosslaps