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临床试验/NCT00606372
NCT00606372Unknown不适用

Aortocoronary Bypasses in High-Risk Patients (EuroSCORE 6+) With or Without Use of the Cardio-Pulmonary Bypass.

Charles University, Czech Republic2 个研究点 分布在 1 个国家目标入组 220 人开始时间: 2006年6月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
220
试验地点
2
主要终点
heart stroke, brain stroke, death, renal failure, early reoperation

研究概览

简要总结

Previous studies comparing on-pump and off-pump operating strategy did only partially demonstrate benefits of the off-pump myocardial revascularisation.In primary end-points (MI, death, renal failure, and so on) there was no significant difference, but in secondary end-points we observed benefits resulting for patients. We would like to show the benefit of the method without extracorporeal circulation in patients with higher and hight operation risk, coming from EuroSCORE classification system (6 points and more).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • stable form of ischemic heart disease
  • unstable angina pectoris
  • acute myocardial infarction
  • additive EuroSCORE 6 and more
  • informed approval of the patient

排除标准

  • significant heart valve disease, requesting surgery
  • aortic aneurysm requesting surgery

结局指标

主要结局

heart stroke, brain stroke, death, renal failure, early reoperation

时间窗: 30 days and 365 days

death, heart stroke, brain stroke, renal failure, early reoperation

时间窗: 30 days

次要结局

  • length of in-hospital stay, blood losses, number of blood-transfusion, new appeared atrial fibrillation, 1-year mortality, quality of life-angina classified by CCS in 1-year follow up, length of mechanical ventilation(30 days and 365 days)

研究者

发起方
Charles University, Czech Republic
申办方类型
Other

研究点 (2)

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