Effectiveness of intra tympanic injection of the mixture of Dexamethason+hyaluronic acid in the treatment of sudden hearing loss.
- Conditions
- Condition 1: Hearing loss. Condition 2: Sudden hearing loss.Sudden idiopathic hearing loss
- Registration Number
- IRCT201611306699N3
- Lead Sponsor
- Vice Chancellor for Research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
The inclusion criteria consisted of unilateral hearing loss (occurring within 72 hours), the hearing threshold average greater than 50 dB, symptoms appearance within 7 days from our intervention, patient's pure tone audiogram at frequencies 250 500, 1000, 2000, 4000 and 8000 Hz, age range 18-80 years, lack of acoustic tumor, middle ear diseases, autoimmune diseases, vestibular problem (Menier disease&..), cardiovascular disorders and diabetes, no history of ear surgery and the patient’s consent to participate in the study.
Meanwhile patient’s refusal to attend on time for follow up visits, any limitation to inject intra tympanum via external auditory canal such as stenosis, anatomical deformities and external and middle ear infections were considered as exclusion criteria.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hearing threshold in different frequencies. Timepoint: Before & two weeks after intervention. Method of measurement: Pure tone audiometry.
- Secondary Outcome Measures
Name Time Method Infection. Timepoint: One week after intervention. Method of measurement: Ear examination.