Prospective Clinical Study to Clarify the Relationship between CYP2D6 Genotype and the Therapeutic Effects of Preoperative Tamoxifen Therapy
Not Applicable
- Conditions
- Breast Cancer
- Registration Number
- JPRN-UMIN000022628
- Lead Sponsor
- Ministry of Health, Labour and Welfare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who meet any of the following criteria are excluded from this clinical study: 1)Non-invasive cancer; 2)Renal dysfunction (dialysis patients with serum creatinine 2.5 mg/dL); 3)Patients with severe hepatic dysfunction (AST, ALT, and total bilirubin levels are all 1.5 or more times the institutional reference range); 4)Patients who are considered to have difficulty in complying with the procedures, observations, etc. specified in the protocol; 5)Patients who are considered to be inappropriate as a subject of this study by the investigator.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in Ki-67 labeling index after tamoxifen treatment
- Secondary Outcome Measures
Name Time Method