Effects of Expectations on Hypoalgesia Produced by Mental Practice

Not Applicable

• Conditions: Cognitive Change
• Interventions: Behavioral: Positive Expectations (initial); Behavioral: Neutral Expectations (during intervention); Behavioral: Neutral Expectations (initial); Behavioral: Negative Expectations (initial); Behavioral: Positive Expectations (during intervention)

• Registration Number: NCT04621162
• Lead Sponsor: Universidad Autonoma de Madrid

Brief Summary

The main objective of this research work is to evaluate and quantify the hypoalgesia generated by motor imagery influenced by the presence of expectations.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-11
• Study First Submitted: 2020-11-03
• Study First Submitted QC: 2020-11-03
• Last Update Submitted: 2020-11-03
• Study First Posted: 2020-11-09
• Last Update Posted: 2020-11-09
• Study Start: 2020-12-30
• Primary Completion: 2021-07-01
• Study Completion: 2021-07-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Age between 18 and 60
• Healthy and with no pain subjects

Exclusion Criteria

• Any cognitive impairment that hindered viewing of audiovisual material.
• Difficulty understanding or communicating.
• Presence of systemic pathology, Central Nervous System or rheumatic disease.
• Inadequate understanding of the Spanish language to follow instructions for measuring and treatment.
• Collaboration of pregnant women.
• Underage subjects
• Subjects with pain at the time of the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Positive Expectations (initial)	Positive Expectations (initial)	-
Neutral Expectations (during intervention)	Neutral Expectations (during intervention)	-
Neutral Expectations (initial)	Neutral Expectations (initial)	-
Negative Expectations (initial)	Negative Expectations (initial)	-
Positive Expectations (during intervention)	Positive Expectations (during intervention)	-

Primary Outcome Measures

Name	Time	Method
Thermal threshold	Change from baseline and immediately post-intervention	This variable will evaluate three aspects. Cold detection threshold, heat detection threshold and heat pain threshold. A specialized and validated instrument is used which consists of a sensor with a resistance that raises and lowers the temperature in a controlled way between 20 and 50ºC.
Pain pressure threshold	Change from baseline and immediately post-intervention	Pressure Pain Threshold (PPT) is one of these tests and it is defined as the minimum force applied which induces pain. The measurement shall be carried out by using an algometer (pressure device that induces mechanical stimuli) is to standardize the amount of pressure applied in the neck region. The reliability of pressure pain thresholds according to raters or measurement frequencies is relatively high.
Heart Rate	Change from baseline and immediately post-intervention	Heart Rate will be measured by three electrodes located in the left area of the chest. One of the electrodes is placed in the middle zone while a second electrode is positioned on the lateral side, and a third one on the lower left side, below the first electrode.

Trial Locations

Locations (1)

CSEU La Salle; 🇪🇸 Madrid, Spain