Relation Entre diabète Gestationnel et Adipocytokines Inflammatoires Chez Des mères obèses et Leur Nouveau-né à l'Accouchement
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Blood levels of leptin in mother and her child
研究概览
简要总结
ADIPOGEST study aims at comparing circulating levels of inflammatory adipocytokins and C-reactive protein in obese women and their newborn at delivery whether exposed or not to Gestational Diabetes Mellitus (GDM)
详细描述
ADIPOGEST is a cross sectional study in which mothers are divided into 2 groups : exposed and unexposed to GDM, matched on pregestational BMI, date of delivery and child gender.
Mothers are recruited in the maternity ward of the University Hospital in South of Reunion Island.
It is planned a conveniance sample of 20 mother-child pairs per group.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pregnant women
- •Obese women (BMI : 30 kg/m² or more)
- •Aged over 18 years
- •With single pregnancy
- •With alive newborn at 37 weeks of amenorrhea or more
- •With informed consent
排除标准
- •Treatments by corticoïds or thyroid hormons
- •Overt diabetes
- •Complicated pregnancy
- •Premature delivery threat
结局指标
主要结局
Blood levels of leptin in mother and her child
时间窗: 2 years
Blood levels of C- Reactive Protein in mother and her child
时间窗: 2 years
Blood levels of adiponectin in mother and her child
时间窗: 2 years
Blood levels of IL-6 in mother and her child
时间窗: 2 years
Blood levels of TNF-alpha in mother and her child
时间窗: 2 years
次要结局
- Blood level of C-peptide in mother(2 years)