Effect of Daily Music Listening on Stroke Recovery
- Conditions
- Stroke
- Registration Number
- NCT01749709
- Lead Sponsor
- Turku University Hospital
- Brief Summary
Single blind randomized clinical trial including 50 stroke patients to investigate the effect of daily music listening on behavioral, neural and physiological recovery. Patients are randomized (1:1:1) to listen instrumental or vocal music, or audiobooks (recorded book reading) (control). Outcome measures are change in neuropsychological tests, change in self-reported mood, structural and functional magnetic resonance imaging changes and hormonal changes performed at acute, 3-month and 6-month stages.
- Detailed Description
Please see above
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- Acute Hemispheral stroke
- Previous neurological or current psychiatric disease,
- severe aphasia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Primary Outcome Measures
Name Time Method Change in neuropsychological performance (verbal memory) From acute to 6-month-stage Verbal memory summary score (RBMT story recall, auditory-verbal learning task)
- Secondary Outcome Measures
Name Time Method Change in neuropsychological performance (Language skill) From acute to 6-month-stages Short Token Test
Change in structural white matter From acute to 6-month stage Diffusion-weighted imaging
Change in physiological stress level From acute to 6-month-stage Oxytocin serum concentration
Change in structural gray matter From acute to 3-month-stage Voxel-based morphometry
Change in mood From acute to 6-month-stage Profile of Mood States
Change in neuronal function From acute to 6-month stage Resting state/task-based fMRI
Change in structural gray matter changes From acute to 6-month-stage Voxel-based morphometry
Trial Locations
- Locations (1)
Turku University Hospital
🇫🇮Turku, Finland
Turku University Hospital🇫🇮Turku, Finland