Effect of Cognitive Stimulation on Recovery After Stroke

Turku University Hospital1 site in 1 country50 target enrollmentDecember 2012

ConditionsStroke

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Stroke
Sponsor: Turku University Hospital
Enrollment: 50
Locations: 1
Primary Endpoint: Change in neuropsychological performance (verbal memory)
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Single blind randomized clinical trial including 50 stroke patients to investigate the effect of daily music listening on behavioral, neural and physiological recovery. Patients are randomized (1:1:1) to listen instrumental or vocal music, or audiobooks (recorded book reading) (control). Outcome measures are change in neuropsychological tests, change in self-reported mood, structural and functional magnetic resonance imaging changes and hormonal changes performed at acute, 3-month and 6-month stages.

Detailed Description

Please see above

Registry

clinicaltrials.gov

Start Date

December 2012

End Date

April 5, 2016

Last Updated

4 years ago

Study Type

Interventional

Study Design

Factorial

Sex

All

Investigators

Sponsor

Turku University Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Acute Hemispheral stroke

Exclusion Criteria

•Previous neurological or current psychiatric disease,
•severe aphasia

Outcomes

Primary Outcomes

Change in neuropsychological performance (verbal memory)

Time Frame: From acute to 6-month-stage

Verbal memory summary score (RBMT story recall, auditory-verbal learning task)

Secondary Outcomes

Change in neuropsychological performance (Language skill)(From acute to 6-month-stages)
Change in structural white matter(From acute to 6-month stage)
Change in physiological stress level(From acute to 6-month-stage)
Change in structural gray matter(From acute to 3-month-stage)
Change in structural gray matter changes(From acute to 6-month-stage)
Change in mood(From acute to 6-month-stage)
Change in neuronal function(From acute to 6-month stage)