跳至主要内容
临床试验/NCT04828278
NCT04828278已完成不适用

Effects of nooLVL Ingestion on Reaction Time and Cognitive Function in Gamers

Texas A&M University2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2020年4月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
2
主要终点
Cognitive Function: Sternberg Task Test

研究概览

简要总结

The purpose of this study is to determine the effects of nooLVL containing arginine and inositol supplementation on executive function and memory prior to and following playing video games.

详细描述

Gaming or "E-Sports" has become a very popular activity particularly among younger individuals. It requires quick reactions, executive function, memory and fine motor skill. In E-Sport competitions and tournaments, E-Sport players often play for hours per session over a series of days. Thus, the ability to maintain cognitive and executive function, concentration and fine motor skill is paramount. Two recent studies have evaluated the effects of ingesting bonded arginine silicate (ASI) and ASI with additional inositol on cognitive function. In the first study, ASI supplementation (1,500 mg/d for 3 days and 14 days) significantly improved the ability to perform complex cognitive tests requiring mental flexibility, processing speed and executive functioning. In the second study, adding 100 mg of inositol to the ASI significantly improved cognitive function in gamers after playing video games for one hour. This study is designed to assess the effects of bonded arginine silicate and inositol ingestion on reaction time and cognitive function prior to and following a 1-hour gaming challenge.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Health Services Research
盲法
Double (Participant, Investigator)

盲法说明

Double Blind

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • They are a healthy male or female Gamer 18 to 40 years of age;
  • They have a Body Mass Index (BMI) between 18 and 34.9 kg/m2;
  • They are willing to supply their own operator-oriented action or stragegy video game that they have played 21 times over the last 3 months and the gaming platform with all accessories needed to play the chosen game;
  • They report no recent ingestion (<2 weeks) of dietary supplements that affect cognitive function including nitrates and nitrous oxide (NO2) promoting supplements;
  • They have a willingness to provide voluntary, written informed consent to participate in the study;

排除标准

  • They have known cardiovascular, metabolic and/or other diseases under the treatment of a physician requiring prescription (Rx) medication (birth control is allowed);
  • They have a history of cognitive dysfunction;
  • They have a known allergy to maltodextrin;
  • They have known allergies or asthma;
  • They have cirrhosis;
  • They have guanidinoacetate methyltransferase deficiency;
  • They have herpes;
  • They have abnormally low blood pressure;
  • They have had a recent heart attack (i.e., within one year);
  • They have kidney disease;
  • They have a surgery scheduled in the next 4-5 weeks;
  • Thye have had a gastrectomy;
  • They have a bipolar disorder;
  • They have an allergy to aspirin or tartrazine products;
  • They are pregnant or breast-feeding or plan to become pregnant in the next 4-5 weeks;

结局指标

主要结局

Cognitive Function: Sternberg Task Test

时间窗: Measured prior to supplementation (Pre-Gaming), and after 15 and 60 minutes (Post-Gaming).

Working Memory Test

Cognitive Function: Cambridge Brain Sciences Reasoning and Concentration Test

时间窗: Measured prior to supplementation (Pre-Gaming), and after 15 and 60 minutes (Post-Gaming).

Reasoning and Concentration Test

Cognitive Function: Light Tracking Reaction Time Test

时间窗: Measured prior to supplementation (Pre-Gaming), and after 15 and 60 minutes (Post-Gaming).

Reaction Time Test

Cognitive Function: Go No-Go Task Test

时间窗: Measured prior to supplementation (Pre-Gaming), and after 15 and 60 minutes (Post-Gaming).

General Attention Test

Cognitive Function: Phychomotor Vigilance Task Test

时间窗: Measured prior to supplementation (Pre-Gaming), and after 15 and 60 minutes (Post-Gaming).

Sustained Attention Test

Cognitive Function: Berg-Washington Card Sorting Task Test

时间窗: Measured prior to supplementation (Pre-Gaming), and after 15 and 60 minutes (Post-Gaming).

Attention Shifting Test

次要结局

  • Stimulant Sensitivity Questionnaire(Measured prior to supplementation (Pre) and after 60 minutes.)
  • Gaming Score and Progression(Measured prior to supplementation (Pre) and after 60 minutes.)
  • Side Effects Questionnaire(Measured prior to supplementation (Pre) and after 60 minutes.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard B. Kreider

Executive Director, Human Clinical Research Facility

Texas A&M University

研究点 (2)

Loading locations...

相似试验

Nutrition21 Study 1 | 临床试验