The effect of return of Del-Nido cardioplegia solution to the extra-corporeal circulation circuit on serum osmolarity variations and clinical outcomes in pediatrics undergoing congenital cardiac defects surgery
Phase 3
Recruiting
- Conditions
- Congenital Heart Disease.Congenital malformations of cardiac chambers and connectionsQ20, Q21,
- Registration Number
- IRCT20240421061549N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
All children with a weight of 5 to 18 kg undergoing heart surgery for congenital defects.
Exclusion Criteria
Absence of written parental consent to enter the study
presence of coagulation disorders before surgery
liver dysfunction with an increase in SGOT or SGPT more than 1.5 times the baseline level before surgery
presence of congenital kidney diseases
death of the child during surgery
need To perform complex surgery
children with RACHS score higher than 2
occurrence of fever resistant to treatment after surgery
occurrence of confirmed sepsis after surgery until the time of admission to ICU
procalcitonin level greater than 0.5 ng/dL with signs of infection
CPB or transverse aortic clamp time more than 120 minutes.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method