Quality of Pain Relief Provided by Infiltration of Morphine Sulphate at the Surgical Wound in Patients Having Spine Fixation Surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/09/057553
- Lead Sponsor
- Sir Ganga Ram Hospital, New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with
-Written informed consent
-Gender: Males and Females
-Age: 18 - 64 years
-Physical Status: ASA grade I/II
Exclusion Criteria
Patients with
-Known renal dysfunction
-Known hepatic dysfunction
-Known endocrinal disease
-History of allergy/hypersensitivity to the drugs under study
-History of substance abuse
-Anticipated postoperative ventilation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain evaluation during first 72 hours as assessed by Numerical rating scale (NRS). <br/ ><br>Timepoint: 30min <br/ ><br>60min <br/ ><br> 90min <br/ ><br> 2hrs <br/ ><br> 6hrs <br/ ><br> 12hrs <br/ ><br> 24hrs <br/ ><br> 48hrs <br/ ><br> 72hrs <br/ ><br>
- Secondary Outcome Measures
Name Time Method <br/ ><br>-Requirement of first rescue analgesia in morphine sulphate & placebo (normal saline) groups from wound infiltration. <br/ ><br>-Supplemental analgesic requirement up to 72 hrs post-surgery in morphine sulphate & placebo groups after wound infiltration. <br/ ><br>-Assessment of side effects like sedation, nausea, & vomiting for 72 hrs post-surgery.Timepoint: ANALGESIC CONSUMPTION OF FENTANYL CITRATE VIA INTRAVENOUS PCA PUMP :at 1st dose then at <br/ ><br>30 min <br/ ><br>60 min <br/ ><br>90 min <br/ ><br>2 hrs <br/ ><br>6 hrs <br/ ><br>12 hrs <br/ ><br>24 hrs <br/ ><br>72 hrs <br/ ><br> <br/ ><br> <br/ ><br>DICLOFENAC SODIUM REQUIREMENT: <br/ ><br>12-24hrs <br/ ><br>24-48 hrs <br/ ><br>48-72 hrs <br/ ><br> <br/ ><br>PONV (postoperative nausea & vomiting) will be assessed at 1 hr, 2 hrs, 6 hrs, 12 hrs, 24 hrs, 48 hrs & 72 hrs <br/ ><br> <br/ ><br>Richmond agitation sedation scale at 1 hr, <br/ ><br>2 hrs, 6 hrs, 12 hrs, 24 hrs, 48 hrs & 72 hrs