A Prospective Randomized Controlled Trial Evaluating the Efficacy and Safety of Ultrasound-Guided Rhomboid Intercostal and Subserratus Plane Block for Enhanced Recovery After Video-Assisted Thoracoscopic Surgery
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Ningbo University
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- 24-hour cumulative number of effective PCA presses
Overview
Brief Summary
This prospective randomized controlled trial evaluates the efficacy and safety of ultrasound-guided rhomboid intercostal and subserratus plane (RISS) block for postoperative analgesia in patients undergoing video-assisted thoracoscopic surgery (VATS).
Postoperative pain after VATS can impair respiratory function, delay mobilization, and increase opioid consumption. Although several regional anesthesia techniques are available, the optimal analgesic strategy remains under investigation. The RISS block is a novel fascial plane block that may provide effective thoracic analgesia while minimizing opioid-related adverse effects.
A total of 90 adult patients scheduled for elective VATS will be randomly assigned to receive either ultrasound-guided RISS block combined with general anesthesia or general anesthesia alone. The primary outcomes include postoperative 24-hour benefit of analgesia score (BCS) and patient-controlled intravenous analgesia (PCIA) pressing frequency. Secondary outcomes include postoperative pain scores, opioid consumption, and adverse events.
This study aims to determine whether RISS block improves postoperative recovery and reduces opioid requirements after VATS.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adults aged 18 years or older
- •ASA physical status I-II
- •Scheduled for elective video-assisted thoracoscopic surgery (VATS)
- •Provided written informed consent
Exclusion Criteria
- •History of shock or coma
- •Coagulopathy
- •Local infection at the puncture site
- •Pre-existing nerve injury on the side intended for block
- •Chronic analgesic use
- •Psychiatric disorders
- •Prior thoracic or breast surgery
- •Allergy to local or general anaesthetic agents
- •Body mass index (BMI) ≥35 kg/m²
- •Inability to operate a patient-controlled analgesia (PCA) device
Arms & Interventions
RISS Block Group
Intervention: Rhomboid Intercostal and Subserratus Plane Block with local anesthetic (Procedure)
ICNB Group
Intervention: Intercostal nerve block (Procedure)
Control Group
Outcomes
Primary Outcomes
24-hour cumulative number of effective PCA presses
Time Frame: Within 24 hours postoperatively
Bruggrmann Comfort Scale (BCS) score at 24 hours
Time Frame: 24 hours after surgery
Secondary Outcomes
No secondary outcomes reported
Investigators
Lei Shi
Professor
Ningbo University