The effect of magnesium supplementation on albuminuria in patient with type 2 diabetic mellitus in Phramongkutklao Hospital : A randomized double-blinded controlled trial

Phase 3

Recruiting

• Conditions: cardiac condition; flushing, Side effects from magnesium e.g diarrhea&#44

• Registration Number: TCTR20200821006
• Lead Sponsor: Phramongkutklao hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-21
• Study Completion: 2021-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

1) Age 30-60 year who have Type2 diabetes mellitus with moderately increased or severely increased albuminuria and have estimated GFR > 60 ml/min/1.73m2
2) serum magnesium level 1.6-2.4 mg/dL
3) on medications (ACEIs, ARBs) for at least 3 month

Exclusion Criteria

1) chronic diarrhea for 3 months
2) taking medications (Proton pump inhibitor)
3) taking other magnesium supplementations e.g Milk of Magnesia, Antacids
4) Alcoholism
5) taking diuretics
6) history of small bowel surgery
7) taking vitamin D supplementation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of albuminuria at 6th month Laboratory measurement

Secondary Outcome Measures

Name	Time	Method
Change of Fasting plasma glucose, HbA1c, BUN, Creatinine, Lipid profile, Urine ICAM at 6th month Laboratory measurement