Detection, quantification and differentiation of upper and lower airway obstruction during mechanical ventilatio

Not Applicable

• Conditions: ung DiseaseCOADAsthma; Lung Disease; COAD; Asthma; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12611000304932
• Lead Sponsor: Intensive care department

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-03-22
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Unconscious patients intubated and mechanically ventilated in intensive care.
1 group with normal lungs and 1 group with Chronic obstructive airways disease or asthma

Exclusion Criteria

Patients not under mechanical ventilation in the intensive care environment

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of airway resistances by analysis of the flow and volume pressure curves from a ventilator. These flow and volumes will be measured after insertion of three progressively decreasing sized endotracheal tubes into already existing endotracheal tubes in an unconscious mechanically ventilated patient.[Immediately after decreasing airway resistance for less than one minute.]

Secondary Outcome Measures

Name	Time	Method
The above measurements will be analysed to determine the best marker for upper and lower airway resistances.[Analysis after ventilatory waveform data has been recorded.]