Effectiveness of oral clonidine as a premedication on intraoperative hemodynamic response for patients undergoing laproscopic cholecystectomy- A Single Blinded Randomised Control Study
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- Intraoperative hemodynamic response( HR, BP, MAP, sevoflurane concentration, total vasopressors used, total amount of fluids given)
研究概览
简要总结
Premedication with oral clonidine suppresses the stressor hormones like catecholamines, cortisol released by laryngoscopy , insertion of laparoscopic ports and provides proper surgical conditions. It also used as analgesic and sedative which improves post operative recovery.
Our study is to evaluate effectiveness of oral clonidine in attenuation of hemodynamic responses in laparoscopic cholecystectomy surgeries
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grading 1 and 2 Elective laproscopic surgery under general anaesthesia.
- •BMI less than 30kg/m2.
排除标准
- •Patient refusal for consent.
- •ASA grading more than
- •BMI more than 30kg/m2.
结局指标
主要结局
Intraoperative hemodynamic response( HR, BP, MAP, sevoflurane concentration, total vasopressors used, total amount of fluids given)
时间窗: Baseline, 1 min after intubation, 5mins after intubation, time of skin incision, at time of pneumoperitoneum, 15 mind after pneumoperitoneum, 15mins after release of pneumoperitoneum.
次要结局
- Postoperative analgesic requirement(VAS SCORES)
研究者
DR KARTIK RAJGOPAL L
Sri Ramachandra medical college and research hospital