Effects of High Intensity Circuit Training and Intermittent Fasting on Polycystic Ovarian Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- PCOS Morphology
研究概览
简要总结
The goal of this randomized controlled trial is to compare the effects of High intensity circuit training, Intermittent Fasting, and their combination on PCOS morphology, Anthropometrics, clinical hyperandrogenism and body image concerns in females with PCOS.
Participants will be divided into three groups who will receive High intensity circuit training, Intermittent fasting and their combination. The outcomes will be PCOS morphology, anthropometrics', clinical hyperandrogenism and body image concerns.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Unmarried females
- •Diagnosed with PCOS Phenotype A based on Rotterdam Criteria:
- •PCOM on US
- •Ovulatory dysfunction
- •Clinical Hyperandrogenism (Hirsutism modified Ferriman Gallway score ≥ 8)
- •Not engaged in any regular lifestyle intervention for <3 Months prior to inclusion
排除标准
- •Use of Estrogen, Progestin or combination.
- •Taking medications or supplements for Insulin resistance < 3 months prior to the inclusion
- •Type I or II DM
- •Hypo/hyperthyroidism
- •BMI ≥27 (Obese according to BMI Asia)
研究组 & 干预措施
High Intensity circuit training (HICT)
For the group allocated with exercise, high intensity circuit training (HICT) of three supervised sessions per week for 20-30 mins will be given. HICT commenced after 10 mins low to moderate intensity warm up and after completing session ended with 10 mins cool down. Intensity of exercise will be measured on borg rating of perceived exertion (RPE). Perceived exertion is how hard you feel like your body is working. Although this is a subjective measure your exertion rating based on a 0 to 10 modified borg rating scale may provide a fairly good estimate of your actual heart rate during physical activity. 0 perceiving "no exertion at all" to 10 perceiving a "maximal exertion" of effort. A moderate intensity activity will be at 3-5 perceiving "somewhat hard", similarly 6-10 will be perceived as high intensity activity.
干预措施: High Intensity Circuit training (HICT) (Other)
Intermittent fasting (IF)
For the group allocated with intermittent fasting, a time restricted feeding (TRF) methodology will be administered. The Fasting protocol will begin with a 12-hour eating window (12:12) and will gradually go down to 8 hours eating window over a period of 8 weeks (16:8).
干预措施: Intermittent Fasting (IF) (Other)
Combination of HICT and IF
The group allocated with both exercise and intermittent fasting will be provided with both HICT for three sessions per week and 8 hours' time restricted eating.
干预措施: Combination of HICT and IF (Other)
结局指标
主要结局
PCOS Morphology
时间窗: 8th Week
Changes from baseline PCOS morphology on the ultrasound will be done by calculating the number of follicles and measuring follicle size. For this purpose, ultrasound imaging is the best option as it is both harmless and inexpensive. PCOS is considered if on ultrasound imaging there are 12 or more than 12 follicles in the ovary and has size of 2-9 mm or volume of 10 cm 3 .
次要结局
- Anthropometrics(8th Week)
- Clinical Hyperandrogenism(8th Week)
- Body Image concerns(8th Week)