Effect of L-carnitine supplementation on metabolic status,leptin and visfatin adipokines in obese diabetic women with hypocaloric diet

Phase 2

Conditions: Condition 1: Diabetic. Condition 2: Obesity.
Non-insulin-dependent diabetes mellitus
obesity

Registration Number: IRCT138903164105N1

Lead Sponsor: Vice-chancellor for Research, Tabriz University Of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 60

Inclusion Criteria

obese women with type2 diabetic; age range 18 to 48years; no cancer, liver or renal disease; receiving any therapeutic diet except diabetes diet; no Pregnancy, lactation and menopause of women.
Exclusion criteria: Consumption of any food supplement or drug which influence carnitine or lipid profile (such as vitamin B6 - C ); treatment with insulin and Failure to follow the prescribed diet.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eptin. Timepoint: baseline, endpoint. Method of measurement: Elisa.;Visfatin. Timepoint: baseline, endpoint. Method of measurement: Elisa.;Anthropometric indicators: weight, body mass index, waist circumference, hip circumference and waist to hip ratio. Timepoint: baseline, endpoint. Method of measurement: Standard procedures using scale, tape and equations.;Body Fat Mass. Timepoint: baseline, endpoint. Method of measurement: Bioimpedance.

Secondary Outcome Measures

Name	Time	Method
FBS. Timepoint: baseline, endpoint. Method of measurement: autoanalyzer.;Insulin resistance: Insulin, HOMA-IR index. Timepoint: baseline, endpoint. Method of measurement: Elisa and formula.;IL-6, hs-CRP. Timepoint: baseline, endpoint. Method of measurement: Elisa and autoanalyzer.;TG. Timepoint: baseline, endpoint. Method of measurement: autoanalyzer.;Cholesterol. Timepoint: baseline, endpoint. Method of measurement: autoanalyzer.;HDL. Timepoint: baseline, endpoint. Method of measurement: autoanalyzer.;Blood pressure. Timepoint: baseline, endpoint. Method of measurement: sphygmomanometer.