Opioid Free versus Opioid Based Anaesthesia on Breast Cancer Pain Score and Immune Response

Not Applicable

• Conditions: Cancer; Anaesthesia

• Registration Number: PACTR201907659337128
• Lead Sponsor: Department of Anesthesia and Pain Management Medical Research Institute Alexandria University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-11
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

American Society of Anesthesiology (ASA) physical status class I and II.

Exclusion Criteria

Patient refusal
Gastroesophageal reflux disease and history of peptic ulcer.
Renal or hepatic impairment.
Reconstructive breast surgery, re-do surgery or previous mastectomy of the other breast.
Coagulopthies
Body Mass Index > 35 kg/m2.
Immunosuppressive therapy and immune disorders.
Metastasis, radiotherapy or chemotherapy before surgery.
Pregnancy.
Patients with a psychiatric disorder.
History of allergy to local anaesthetics.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity using the Visual Analogue Scale (VAS) in the first 24 hours postoperatively.<br>;Screening for post-mastectomy neuropathic pain.

Secondary Outcome Measures

Name	Time	Method
Effect of opioid and surgical stress on the immune system.<br>