JPRN-jRCTs031180339招募中2 期
Exploratory study on the anti-proliferative effects of metformin on endometrial cancer
Habu Yuji0 个研究点目标入组 15 人开始时间: 2019年3月18日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 15
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 60age old（—）
- 性别
- Female
入选标准
- •1.Histologically confirmed grade 1-2 endometrioid adenocarcinoma
- •2.BMI over 25 and positive for insulin resistance
- •3.Over 20 years and under 60 years of age
- •4.Eastern Cooperative Oncology Group Performance status 0
- •5.Patient who are ready to provide written informed consent
排除标准
- •1. Prior medical history of chemical sensitivity to metformin
- •2. Serum creatinine over1.0 mg/dl
- •3.History of lactic acidosis
- •4.Patients undergoing dialysis
- •5.Shock, cardiac arrest, cardiac infarction, thrombosis of the lung, or severe cardiovascular and/or lung damage
- •6.Ingestion of excessive amounts of alcohol
- •7.Elevated levels of AST(GOT), ALT(GPT) (over2 times upper limit of normal)
- •8.History of thrombosis
- •9.Mental illness that may require the administration of antipsychotics
- •10.Diabetes mellitus that requires medication
- •11.HbA1c over 8.0
- •12.Concomitant malignancies
- •13.Determined to be ineligible by the physician in charge for any other reason
研究者
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