NCT02281851已完成不适用
The Effects of Habitual Antioxidant Supplementation on Endogenous Antioxidants and Oxidative Damage in Well Trained Cyclists
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Difference in Resting Levels of Endogenous Antioxidant Proteins in Skeletal Muscle - Superoxide Dismutase 2 (SOD-2)
研究概览
简要总结
This study will investigate whether increased habitual intake of antioxidant supplements effects the concentration of endogenous antioxidants, the response of antioxidants to exercise, and differences in oxidative damage compared to a non-supplemented group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI 18.8 29.9 kg/m2
- •cycle 3-7 times a week for durations longer than 60 minutes
- •cycled for a minimum of 3 years
- •accustomed to exhaustive cycling protocols
- •healthy (no known cardiovascular or metabolic disease)
排除标准
- •answering "NO" to any question on the general health questionnaire would result in exclusion from the study
- •current participation in another clinical study
- •current or recent smoker (last 30 days)
- •prescription or non-prescription of anti-inflammatory use >30 days prior to the experiment commencing or any other medications that in the opinion of the investigator may interfere with redox signalling
结局指标
主要结局
Difference in Resting Levels of Endogenous Antioxidant Proteins in Skeletal Muscle - Superoxide Dismutase 2 (SOD-2)
时间窗: Protein concentrations will be measured at baseline only
To examine the effects of habitual vitamin and antioxidant supplementation on endogenous antioxidant production, participants will have a muscle biopsy taken at rest to examine any differences in endogenous antioxidant protein concentrations
次要结局
未报告次要终点
研究者
研究点 (1)
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