EUCTR2010-019296-30-GB进行中（未招募）不适用
A pharmacokinetic and pharmacodynamic study of recombinant human IGF-I (rhIGF-I) in three boys with ALS deficiency, and insulin sensitivity and bone density in patients and heterozygous first-degree relatives. - ALS deficiency: insulin resistance, bone strength & response to rhIGF1
niversity Hospital Birmingham NHS Foundation Trust0 个研究点开始时间: 2010年4月16日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •PK/PD study arm: Patients with confirmed IGFALS gene mutations, able to give informed consent
- •Cross-sectional study arm: Heterozygous first-degree relatives, able to give informed consent.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •PK/PD study arm: Patients currently receiving IncrelexTM treatment, patients allergic to Increlex, patients with cancer
- •Cross-sectional study arm: Individuals suffering from cancer or chronic inflammatory conditions (e.g. chronic rheumatoid arthritis, inflammatory bowels disease).
研究者
相似试验
进行中（未招募）
1 期
Combined growth hormone and IGF1 therapy in paediatric Crohn'd diseaseImpaired growth in Paediatric Crohn's diseaseMedDRA version: 14.1Level: LLTClassification code 10011398Term: Crohn'sSystem Organ Class: 100000004856EUCTR2010-022215-19-GBGreater Glasgow & Clyde NHS24
进行中（未招募）
1 期
Evaluation of the pharmacodynamic effects of riociguat in subjects with pulmonary hypertension and heart failure with preserved ejection fraction in a randomized, double blind, placebo controlled, parallel group, multicenter studyEUCTR2014-003055-60-ATMedical University of Vienna90
进行中（未招募）
1 期
Evaluation of the pharmacodynamic effects of riociguat in subjects with pulmonary hypertension and heart failure with preserved ejection fraction in a randomized, double blind, placebo controlled, parallel group, multicenter studyPulmonary hypertension and heart failure with preserved ejectionfractionEUCTR2014-003055-60-DEMedical University of Vienna114
进行中（未招募）
1 期
Pharmacokinetic and pharmacodynamic evaluation of linezolid administered intravenously in MRSA-positive, morbidly obese patients with pneumonia.EUCTR2012-005127-33-BEniversity Ghent20
已完成
不适用
Pharmacokinetic and pharmacodynamic modelling of routinely used off label drugs in premature neonates10039911Pijn en sedatiePrematurity10028971NL-OMON44214Erasmus MC, Universitair Medisch Centrum Rotterdam600